Endocrine Abstracts

Background: It is not known if non-functional adrenal adenomas (NFAA) are associated with increased mortality.Objective: To investigate mortality in patients with NFAA and compare with matched controls. Design: Retrospective register-based national cohort study.Methods: Patients diagnosed with NFAA in Sweden 2005-2019 were identified and followed until death or 2020. For each case, four age/sex/municipality-m...

Importance: It is not known if non-functional adrenal tumors (NFATs) are associated with dementia.Objective: To analyze incidence and prevalence of dementia in individuals with NFAT.Design, setting and participants: A national retrospective register-based study in patients with NFAT diagnosed in Sweden 2005–2019 and controls without adrenal tumors followed until death or end of 2019 was conducted. Individuals with a diagnosis ...

Adrenal tumors (ATs) are uncommon in children and adolescents. The aim of this nation-wide retrospective registry-based cohort study was to characterise the various ATs in this population and demonstrate their differences from ATs in adults. All patients under the age of 21 in Sweden with verified adrenal lesions according to ICD-codes between 2005 and 2019 were identified in linked nation-wide registries. Out of the total 232 patients, 121 (52.2%) were boys, with boy predomin...

Importance: It is unclear if non-functional adrenal tumors (NFAT) are associated with higher cancer incidence.Objective: To analyze the cancer incidence in patients with NFAT.Design, Settings and Participants: A national retrospective register-based study involving cases with NFAT diagnosed in Sweden 2005-2019 and controls was conducted. Both cases and controls were followed until death or 2020. Individuals with diagnosed adrenal h...

Objective: Hyponatremia is associated with considerable morbidity, and mortality but causal links have been difficult to establish. Here, we describe the establishment and representativeness of the Stockholm Sodium Cohort (SSC), designed to study etiologies and outcomes of hyponatremia.Study, Design and Setting: All residents of Stockholm County, undertaking at least one serum sodium test between 2005-2018 were included in the SSC. Individual-level test ...